Tissue-on-Chip/3D Organoids

Tumor and tumor associated microenvironment created in a microfluidic deviceDevelopment of three-dimensional (3D) cell cultures has not only advanced regenerative medicine but also led to the development of physiologically relevant model systems to understand the interdependency between cells and their microenvironment as well as various cellular functions leading to tissue formation. Engineered 3D tissues could also be used as ex vivo technological platform for drug and small molecule discovery and development. Employing hiPSCs as cell source further allows the use of such platforms towards personalize medicine.