Publications

2024

Hainline, Kelly M., Helena Freire Haddad, Anna Gilpin, Elizabeth J. Curvino, Shyni Varghese, and Joel H. Collier. “Active immunotherapy for C5a-mediated inflammation using adjuvant-free self-assembled peptide nanofibers.” Acta Biomater 179 (April 15, 2024): 83–94. https://doi.org/10.1016/j.actbio.2024.02.042.

Cottrill, Ethan, Zach Pennington, Nathan Sattah, Crystal Jing, Dave Salven, Eli Johnson, Max Downey, Shyni Varghese, Brett Rocos, and William Richardson. “Gene Therapy and Spinal Fusion: Systematic Review and Meta-analysis of the Available Data.” World Neurosurg, April 5, 2024. https://doi.org/10.1016/j.wneu.2024.03.174.

Price, Meghan J., Annee D. Nguyen, Corinne Haines, César D. Baëta, Jovita Byemerwa, Debarati Murkajee, Sandeep Artham, et al. “UDP-6-glucose dehydrogenase in hormonally responsive breast cancers.” BioRxiv, March 21, 2024. https://doi.org/10.1101/2024.03.20.585919.

Natesh, Naveen R., Pankaj Mogha, Alan Chen, Scott J. Antonia, and Shyni Varghese. “Differential roles of normal and lung cancer-associated fibroblasts in microvascular network formation.” APL Bioeng 8, no. 1 (March 2024): 016120. https://doi.org/10.1063/5.0188238.

Subramaniam, Shankar, Metin Akay, Mark A. Anastasio, Vasudev Bailey, David Boas, Paolo Bonato, Ashutosh Chilkoti, et al. “Grand Challenges at the Interface of Engineering and Medicine.” IEEE Open J Eng Med Biol 5 (2024): 1–13. https://doi.org/10.1109/OJEMB.2024.3351717.

2023

Shih, Yu-Ru V., David Kingsley, Hunter Newman, Jiaul Hoque, Ankita Gupta, B Duncan X. Lascelles, and Shyni Varghese. “Multi-Functional Small Molecule Alleviates Fracture Pain and Promotes Bone Healing.” Adv Sci (Weinh) 10, no. 36 (December 2023): e2303567. https://doi.org/10.1002/advs.202303567.

Guo, Wendi, Jiaul Hoque, Carolina J. Garcia Garcia, Kassandra V. Spiller, Abigail P. Leinroth, Vijitha Puviindran, Cahil K. Potnis, et al. “Radiation-induced bone loss in mice is ameliorated by inhibition of HIF-2α in skeletal progenitor cells.” Sci Transl Med 15, no. 724 (November 29, 2023): eabo5217. https://doi.org/10.1126/scitranslmed.abo5217.

Cigliola, Valentina, Adam Shoffner, Nutishia Lee, Jianhong Ou, Trevor J. Gonzalez, Jiaul Hoque, Clayton J. Becker, et al. “Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer.” Nat Commun 14, no. 1 (August 11, 2023): 4857. https://doi.org/10.1038/s41467-023-40486-5.

Gonzales, G., S. Zauscher, and S. Varghese. “Progress in the design and synthesis of viscosupplements for articular joint lubrication.” Current Opinion in Colloid and Interface Science 66 (August 1, 2023). https://doi.org/10.1016/j.cocis.2023.101708.

Aung, Aereas, Shruti K. Davey, Jomkuan Theprungsirikul, Vardhman Kumar, and Shyni Varghese. “Deciphering the Mechanics of Cancer Spheroid Growth in 3D Environments through Microfluidics Driven Mechanical Actuation.” Adv Healthc Mater 12, no. 14 (June 2023): e2201842. https://doi.org/10.1002/adhm.202201842.

Newman, Hunter, and Shyni Varghese. “Extracellular adenosine signaling in bone health and disease.” Curr Opin Pharmacol 70 (June 2023): 102378. https://doi.org/10.1016/j.coph.2023.102378.

Rana, Isha, Sunny Kataria, Tuan Lin Tan, Edries Yousaf Hajam, Deepak Kumar Kashyap, Dyuti Saha, Johan Ajnabi, et al. “Mindin (SPON2) Is Essential for Cutaneous Fibrogenesis in a Mouse Model of Systemic Sclerosis.” J Invest Dermatol 143, no. 5 (May 2023): 699-710.e10. https://doi.org/10.1016/j.jid.2022.10.011.

Kumar, Vardhman, David Kingsley, Sajeeshkumar Madhurakkat Perikamana, Pankaj Mogha, C Rory Goodwin, and Shyni Varghese. “Self-assembled innervated vasculature-on-a-chip to study nociception.” Biofabrication 15, no. 3 (April 13, 2023). https://doi.org/10.1088/1758-5090/acc904.

Yang, Ting, Ravikanth Velagapudi, Cuicui Kong, Unghyeon Ko, Vardhman Kumar, Paris Brown, Nathan O. Franklin, et al. “Protective effects of omega-3 fatty acids in a blood-brain barrier-on-chip model and on postoperative delirium-like behaviour in mice.” Br J Anaesth 130, no. 2 (February 2023): e370–80. https://doi.org/10.1016/j.bja.2022.05.025.

Gonzales, G., J. Hoque, A. Gilpin, B. Maity, S. Zauscher, and S. Varghese. “Branched poly-l-lysine for cartilage penetrating carriers.” Bioengineering and Translational Medicine, January 1, 2023. https://doi.org/10.1002/btm2.10612.

Varghese, Shyni. “BIOENGINEERED PLATFORM TO STUDY IMMUNE-CANCER CELL INTERACTIONS EX VIVO.” In TISSUE ENGINEERING PART A, 29:138–138, 2023.

Guo, Wendi, Jiaul Hoque, Carolina Garcia, Kassandra Spiller, Tara Fujimoto, Denae Johnson, Abagail Delahoussaye, et al. “Targeting HIF-2 in the bone marrow microenvironment as a radioprotective strategy for bone.” In JOURNAL OF BONE AND MINERAL RESEARCH, 38:3–3, 2023.

2022

Hoque, Jiaul, Yuze Zeng, Hunter Newman, Gavin Gonzales, Cheryl Lee, and Shyni Varghese. “Microgel-Assisted Delivery of Adenosine to Accelerate Fracture Healing.” ACS Biomater Sci Eng 8, no. 11 (November 14, 2022): 4863–72. https://doi.org/10.1021/acsbiomaterials.2c00977.

Chansoria, P., J. Blackwell, E. L. Etter, E. E. Bonacquisti, N. Jasiewicz, T. Neal, S. A. Kamal, et al. “Rationally Designed Anisotropic and Auxetic Hydrogel Patches for Adaptation to Dynamic Organs.” Advanced Functional Materials 32, no. 43 (October 1, 2022). https://doi.org/10.1002/adfm.202207590.

Newman, Hunter, Jiaul Hoque, Yu-Ru V. Shih, Gabrielle Marushack, Unghyeon Ko, Gavin Gonzales, and Shyni Varghese. “pH-Sensitive nanocarrier assisted delivery of adenosine to treat osteoporotic bone loss.” Biomater Sci 10, no. 18 (September 13, 2022): 5340–55. https://doi.org/10.1039/d2bm00843b.

Bartholf DeWitt, Suzanne, Sarah Hoskinson Plumlee, Hailey E. Brighton, Dharshan Sivaraj, E. J. Martz, Maryam Zand, Vardhman Kumar, et al. “Loss of ATRX promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin binding.” JCI Insight 7, no. 17 (September 8, 2022). https://doi.org/10.1172/jci.insight.151583.

Perikamana, Sajeesh Kumar Madhurakkat, Nailah Seale, Jiaul Hoque, Ji Hyun Ryu, Vardhman Kumar, Yuru Vernon Shih, and Shyni Varghese. “Molecularly Tailored Interface for Long-Term Xenogeneic Cell Transplantation.” Adv Funct Mater 32, no. 4 (January 19, 2022). https://doi.org/10.1002/adfm.202108221.

Kumar, Vardhman, Sajeesh Kumar Madhurakkat Perikamana, Aleksandra Tata, Jiaul Hoque, Anna Gilpin, Purushothama Rao Tata, and Shyni Varghese. “An In Vitro Microfluidic Alveolus Model to Study Lung Biomechanics.” Front Bioeng Biotechnol 10 (2022): 848699. https://doi.org/10.3389/fbioe.2022.848699.

Ko, Ung Hyun, Vardhman Kumar, Benjamin Rosen, and Shyni Varghese. “Characterization of bending balloon actuators.” Front Robot AI 9 (2022): 991748. https://doi.org/10.3389/frobt.2022.991748.

2021

Gilpin, Anna, Yuze Zeng, Jiaul Hoque, Ji Hyun Ryu, Yong Yang, Stefan Zauscher, William Eward, and Shyni Varghese. “Self-Healing of Hyaluronic Acid to Improve In Vivo Retention and Function.” Adv Healthc Mater 10, no. 23 (December 2021): e2100777. https://doi.org/10.1002/adhm.202100777.