Publications

Kumar, Vardhman, and Shyni Varghese. “Ex Vivo Tumor-on-a-Chip Platforms to Study Intercellular Interactions within the Tumor Microenvironment.” Adv Healthc Mater 8, no. 4 (February 2019): e1801198. https://doi.org/10.1002/adhm.201801198.

Hoque, Jiaul, Nivedita Sangaj, and Shyni Varghese. “Stimuli-Responsive Supramolecular Hydrogels and Their Applications in Regenerative Medicine.” Macromol Biosci 19, no. 1 (January 2019): e1800259. https://doi.org/10.1002/mabi.201800259.

Ryu, Ji Hyun, Gyeong Jin Lee, Yu-Ru V. Shih, Tae-Il Kim, and Shyni Varghese. “Phenylboronic Acid-polymers for Biomedical Applications.” Curr Med Chem 26, no. 37 (2019): 6797–6816. https://doi.org/10.2174/0929867325666181008144436.

Liu, Mengqian, Manando Nakasaki, Yu-Ru Vernon Shih, and Shyni Varghese. “Effect of age on biomaterial-mediated in situ bone tissue regeneration.” Acta Biomater 78 (September 15, 2018): 329–40. https://doi.org/10.1016/j.actbio.2018.06.035.

Kang, Heemin, Yuze Zeng, and Shyni Varghese. “Functionally graded multilayer scaffolds for in vivo osteochondral tissue engineering.” Acta Biomater 78 (September 15, 2018): 365–77. https://doi.org/10.1016/j.actbio.2018.07.039.

Seale, Nailah, Suvasini Ramaswamy, Yu-Ru Shih, Inder Verma, and Shyni Varghese. “Macroporous Dual-compartment Hydrogels for Minimally Invasive Transplantation of Primary Human Hepatocytes.” Transplantation 102, no. 9 (September 2018): e373–81. https://doi.org/10.1097/TP.0000000000002330.

Moreno, Ana M., Xin Fu, Jie Zhu, Dhruva Katrekar, Yu-Ru V. Shih, John Marlett, Jessica Cabotaje, et al. “In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation.” Mol Ther 26, no. 7 (July 5, 2018): 1818–27. https://doi.org/10.1016/j.ymthe.2018.04.017.

González Díaz, Eva C., Yu-Ru V. Shih, Manando Nakasaki, Mengqian Liu, and Shyni Varghese. “Mineralized Biomaterials Mediated Repair of Bone Defects Through Endogenous Cells.” Tissue Eng Part A 24, no. 13–14 (July 2018): 1148–56. https://doi.org/10.1089/ten.TEA.2017.0297.

Seale, Nailah, Yuze Zeng, and S. Varghese. “Biomimetic Tissue Engineering for Musculoskeletal Tissues.” edited by Martin Stoddart, April Craft, Girish Pattappa, and Oliver Gardner, 2018. https://doi.org/10.1016/B978-0-12-811467-4.00009-7.

Kang, Heemin, Yu-Ru V. Shih, and Shyni Varghese. “Direct Conversion of Human Pluripotent Stem Cells to Osteoblasts With a Small Molecule.” Curr Protoc Stem Cell Biol 44 (February 28, 2018): 1F.21.1-1F.21.6. https://doi.org/10.1002/cpsc.44.

Varghese, Shyni. “Role of Matrix Proteins in Balancing Tissue Stiffness and Inflammation in Fibrosis.” In BIOPHYSICAL JOURNAL, 114:23A-23A. CELL PRESS, 2018.

Phadke, A., and S. Varghese. “Synthetic Biomaterials and Stem Cells for Connective Tissue Engineering.” In Molecular Cellular and Tissue Engineering, 36-36–18, 2018.

Hwang, Yongsung, Timothy Seo, Sara Hariri, Chulmin Choi, and Shyni Varghese. “Matrix Topographical Cue-Mediated Myogenic Differentiation of Human Embryonic Stem Cell Derivatives.” Polymers (Basel) 9, no. 11 (November 5, 2017). https://doi.org/10.3390/polym9110580.

Agrawal, Gaurav, Aereas Aung, and Shyni Varghese. “Skeletal muscle-on-a-chip: an in vitro model to evaluate tissue formation and injury.” Lab Chip 17, no. 20 (October 11, 2017): 3447–61. https://doi.org/10.1039/c7lc00512a.

Shih, Yu-Ru, Heemin Kang, Vikram Rao, Yu-Jui Chiu, Seong Keun Kwon, and Shyni Varghese. “In vivo engineering of bone tissues with hematopoietic functions and mixed chimerism.” Proc Natl Acad Sci U S A 114, no. 21 (May 23, 2017): 5419–24. https://doi.org/10.1073/pnas.1702576114.

Kang, H., Y. R. V. Shih, V. Rao, and S. Varghese. “Biomineralized matrices as intelligent scaffolds for bone tissue regeneration.” In Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine 2nd Edition, 59–84, 2017. https://doi.org/10.1201/9781315364698.

González-Díaz, E. C., and S. Varghese. “Hydrogels as extracellular matrix analogs.” Gels 2, no. 3 (September 1, 2016). https://doi.org/10.3390/gels2030020.

Kang, Heemin, Yu-Ru V. Shih, Manando Nakasaki, Harsha Kabra, and Shyni Varghese. “Small molecule-driven direct conversion of human pluripotent stem cells into functional osteoblasts.” Sci Adv 2, no. 8 (August 2016): e1600691. https://doi.org/10.1126/sciadv.1600691.

Mo, Alexander H., Preston B. Landon, Karla Santacruz Gomez, Heemin Kang, Joon Lee, Chen Zhang, Woraphong Janetanakit, et al. “Magnetically-responsive silica-gold nanobowls for targeted delivery and SERS-based sensing.” Nanoscale 8, no. 23 (June 9, 2016): 11840–50. https://doi.org/10.1039/c6nr02445a.

Aung, Aereas, Jomkuan Theprungsirikul, Han Liang Lim, and Shyni Varghese. “Chemotaxis-driven assembly of endothelial barrier in a tumor-on-a-chip platform.” Lab Chip 16, no. 10 (May 21, 2016): 1886–98. https://doi.org/10.1039/c6lc00184j.

Wen, Cai, Heemin Kang, Yu-Ru V. Shih, YongSung Hwang, and Shyni Varghese. “In vivo comparison of biomineralized scaffold-directed osteogenic differentiation of human embryonic and mesenchymal stem cells.” Drug Deliv Transl Res 6, no. 2 (April 2016): 121–31. https://doi.org/10.1007/s13346-015-0242-2.

Sharma, Blanka, and Shyni Varghese. “Progress in orthopedic biomaterials and drug delivery.” Drug Deliv Transl Res 6, no. 2 (April 2016): 75–76. https://doi.org/10.1007/s13346-016-0288-9.

Aung, Aereas, Ivneet Singh Bhullar, Jomkuan Theprungsirikul, Shruti Krishna Davey, Han Liang Lim, Yu-Jui Chiu, Xuanyi Ma, et al. “3D cardiac μtissues within a microfluidic device with real-time contractile stress readout.” Lab Chip 16, no. 1 (January 7, 2016): 153–62. https://doi.org/10.1039/c5lc00820d.

Seale, N. M., and S. Varghese. “Biomaterials for pluripotent stem cell engineering: From fate determination to vascularization.” Journal of Materials Chemistry B 4, no. 20 (January 1, 2016): 3454–63. https://doi.org/10.1039/c5tb02658j.

Kar, Mrityunjoy, Yu-Ru Vernon Shih, Daniel Ortiz Velez, Pedro Cabrales, and Shyni Varghese. “Poly(ethylene glycol) hydrogels with cell cleavable groups for autonomous cell delivery.” Biomaterials 77 (January 2016): 186–97. https://doi.org/10.1016/j.biomaterials.2015.11.018.