Publications

Nguyen, Quynhhoa T., Yongsung Hwang, Albert C. Chen, Shyni Varghese, and Robert L. Sah. “Cartilage-like mechanical properties of poly (ethylene glycol)-diacrylate hydrogels.” Biomaterials 33, no. 28 (October 2012): 6682–90. https://doi.org/10.1016/j.biomaterials.2012.06.005.

Phadke, Ameya, Yu-Ru V. Shih, and Shyni Varghese. “Mineralized synthetic matrices as an instructive microenvironment for osteogenic differentiation of human mesenchymal stem cells.” Macromol Biosci 12, no. 8 (August 2012): 1022–32. https://doi.org/10.1002/mabi.201100289.

Varghese, S., and C. Jamora. “Hydrogels: A versatile tool with a myriad of biomedical and research applications for the skin.” Expert Review of Dermatology 7, no. 4 (August 1, 2012): 315–17. https://doi.org/10.1586/edm.12.28.

Soman, Pranav, Jin Woo Lee, Ameya Phadke, Shyni Varghese, and Shaochen Chen. “Spatial tuning of negative and positive Poisson's ratio in a multi-layer scaffold.” Acta Biomater 8, no. 7 (July 2012): 2587–94. https://doi.org/10.1016/j.actbio.2012.03.035.

Soman, P., D. Y. Fozdar, J. W. Lee, A. Phadke, S. Varghese, and S. Chen. “A three-dimensional polymer scaffolding material exhibiting a zero Poisson's ratio.” Soft Matter 8, no. 18 (May 14, 2012): 4946–51. https://doi.org/10.1039/c2sm07354d.

Phadke, Ameya, Chao Zhang, Bedri Arman, Cheng-Chih Hsu, Raghunath A. Mashelkar, Ashish K. Lele, Michael J. Tauber, Gaurav Arya, and Shyni Varghese. “Rapid self-healing hydrogels.” Proc Natl Acad Sci U S A 109, no. 12 (March 20, 2012): 4383–88. https://doi.org/10.1073/pnas.1201122109.

Varghese, S., and A. J. Engler. “Musculoskeletal cell mechanics.” In Orthopaedic Biomechanics, 301–23, 2012. https://doi.org/10.1201/b13733.

Sangaj, N., and S. Varghese. “Controlling stem cells with biomaterials.” In Biomaterials for Tissue Engineering Applications: A Review of the Past and Future Trends, 511–38, 2011. https://doi.org/10.1007/978-3-7091-0385-2_18.

Zhang, Chao, Nivedita Sangaj, Yongsung Hwang, Ameya Phadke, Chien-Wen Chang, and Shyni Varghese. “Oligo(trimethylene carbonate)-poly(ethylene glycol)-oligo(trimethylene carbonate) triblock-based hydrogels for cartilage tissue engineering.” Acta Biomater 7, no. 9 (September 2011): 3362–69. https://doi.org/10.1016/j.actbio.2011.05.024.

Hwang, Yongsung, Ameya Phadke, and Shyni Varghese. “Engineered microenvironments for self-renewal and musculoskeletal differentiation of stem cells.” Regen Med 6, no. 4 (July 2011): 505–24. https://doi.org/10.2217/rme.11.38.

Lin, Susan, Nivedita Sangaj, Tojo Razafiarison, Chao Zhang, and Shyni Varghese. “Influence of physical properties of biomaterials on cellular behavior.” Pharm Res 28, no. 6 (June 2011): 1422–30. https://doi.org/10.1007/s11095-011-0378-9.

Ayala, Ramses, Chao Zhang, Darren Yang, Yongsung Hwang, Aereas Aung, Sumeet S. Shroff, Fernando T. Arce, Ratnesh Lal, Gaurav Arya, and Shyni Varghese. “Engineering the cell-material interface for controlling stem cell adhesion, migration, and differentiation.” Biomaterials 32, no. 15 (May 2011): 3700–3711. https://doi.org/10.1016/j.biomaterials.2011.02.004.

Gillies, Allison R., Lucas R. Smith, Richard L. Lieber, and Shyni Varghese. “Method for decellularizing skeletal muscle without detergents or proteolytic enzymes.” Tissue Eng Part C Methods 17, no. 4 (April 2011): 383–89. https://doi.org/10.1089/ten.TEC.2010.0438.

Lim, Han L., Jessica C. Chuang, Tuan Tran, Aereas Aung, Gaurav Arya, and Shyni Varghese. “Dynamic Electromechanical Hydrogel Matrices for Stem Cell Culture.” Adv Funct Mater 21, no. 1 (January 7, 2011). https://doi.org/10.1002/adfm.201001519.

Hwang, N. S., S. Varghese, H. Li, and J. Elisseeff. “Regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells in PEG-ECM hydrogels.” Cell and Tissue Research 344, no. 3 (January 1, 2011): 499–509. https://doi.org/10.1007/s00441-011-1153-2.

Neiman, V. J., and S. Varghese. “Synthetic bio-actuators and their applications in biomedicine.” Smart Structures and Systems 7, no. 3 (January 1, 2011): 185–98. https://doi.org/10.12989/sss.2011.7.3.185.

Aung, Aereas, Gunjan Gupta, Ghassemian Majid, and Shyni Varghese. “Osteoarthritic chondrocyte-secreted morphogens induce chondrogenic differentiation of human mesenchymal stem cells.” Arthritis Rheum 63, no. 1 (January 2011): 148–58. https://doi.org/10.1002/art.30086.

Sangaj, Nivedita, Phillip Kyriakakis, Darren Yang, Chien-Wen Chang, Gaurav Arya, and Shyni Varghese. “Heparin mimicking polymer promotes myogenic differentiation of muscle progenitor cells.” Biomacromolecules 11, no. 12 (December 13, 2010): 3294–3300. https://doi.org/10.1021/bm101041f.

Brafman, David A., Chien W. Chang, Antonio Fernandez, Karl Willert, Shyni Varghese, and Shu Chien. “Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces.” Biomaterials 31, no. 34 (December 2010): 9135–44. https://doi.org/10.1016/j.biomaterials.2010.08.007.

Chang, C. W., A. Van Spreeuwel, C. Zhang, and S. Varghese. “PEG/clay nanocomposite hydrogel: A mechanically robust tissue engineering scaffold.” Soft Matter 6, no. 20 (October 21, 2010): 5157–64. https://doi.org/10.1039/c0sm00067a.

Hwang, Yongsung, Nivedita Sangaj, and Shyni Varghese. “Interconnected macroporous poly(ethylene glycol) cryogels as a cell scaffold for cartilage tissue engineering.” Tissue Eng Part A 16, no. 10 (October 2010): 3033–41. https://doi.org/10.1089/ten.TEA.2010.0045.

Phadke, Ameya, Chao Zhang, Yongsung Hwang, Kenneth Vecchio, and Shyni Varghese. “Templated mineralization of synthetic hydrogels for bone-like composite materials: role of matrix hydrophobicity.” Biomacromolecules 11, no. 8 (August 9, 2010): 2060–68. https://doi.org/10.1021/bm100425p.

Brammer, K. S., S. Oh, C. J. Frandsen, S. Varghese, and S. Jin. “Nanotube surface triggers increased chondrocyte extracellular matrix production.” Materials Science and Engineering C 30, no. 4 (May 10, 2010): 518–25. https://doi.org/10.1016/j.msec.2010.01.013.

Varghese, Shyni, Nathaniel S. Hwang, Angela Ferran, Alexander Hillel, Parnduangjai Theprungsirikul, Adam C. Canver, Zijun Zhang, John Gearhart, and Jennifer Elisseeff. “Engineering musculoskeletal tissues with human embryonic germ cell derivatives.” Stem Cells 28, no. 4 (April 2010): 765–74. https://doi.org/10.1002/stem.325.

Hwang, Y., C. Zhang, and S. Varghese. “Poly(ethylene glycol) cryogels as potential cell scaffolds: Effect of polymerization conditions on cryogel microstructure and properties.” Journal of Materials Chemistry 20, no. 2 (January 1, 2010): 345–51. https://doi.org/10.1039/b917142h.