Publications

Kang, Heemin, Yu-Ru V. Shih, and Shyni Varghese. “Biomineralized matrices dominate soluble cues to direct osteogenic differentiation of human mesenchymal stem cells through adenosine signaling.” Biomacromolecules 16, no. 3 (March 9, 2015): 1050–61. https://doi.org/10.1021/acs.biomac.5b00099.

Kim, Hwan D., Jiseung Heo, Yongsung Hwang, Seon-Yeong Kwak, Ok Kyu Park, Hyunbum Kim, Shyni Varghese, and Nathaniel S. Hwang. “Extracellular-matrix-based and Arg-Gly-Asp-modified photopolymerizing hydrogels for cartilage tissue engineering.” Tissue Eng Part A 21, no. 3–4 (February 2015): 757–66. https://doi.org/10.1089/ten.TEA.2014.0233.

Kabra, Harsha, Yongsung Hwang, Han Liang Lim, Mrityunjoy Kar, Gaurav Arya, and Shyni Varghese. “Biomimetic Material-Assisted Delivery of Human Embryonic Stem Cell Derivatives for Enhanced In Vivo Survival and Engraftment.” ACS Biomater Sci Eng 1, no. 1 (January 12, 2015): 7–12. https://doi.org/10.1021/ab500021a.

Rao, V., Y. R. V. Shih, H. Kang, H. Kabra, and S. Varghese. “Adenosine signaling mediates osteogenic differentiation of human embryonic stem cells on mineralized matrices.” Frontiers in Bioengineering and Biotechnology 3, no. NOV (January 1, 2015). https://doi.org/10.3389/fbioe.2015.00185.

Aung, Aereas, Young N. Seo, Shaoying Lu, Yingxiao Wang, Colin Jamora, Juan C. del Álamo, and Shyni Varghese. “3D traction stresses activate protease-dependent invasion of cancer cells.” Biophys J 107, no. 11 (December 2, 2014): 2528–37. https://doi.org/10.1016/j.bpj.2014.07.078.

Kang, Heemin, Yu-Ru V. Shih, Yongsung Hwang, Cai Wen, Vikram Rao, Timothy Seo, and Shyni Varghese. “Mineralized gelatin methacrylate-based matrices induce osteogenic differentiation of human induced pluripotent stem cells.” Acta Biomater 10, no. 12 (December 2014): 4961–70. https://doi.org/10.1016/j.actbio.2014.08.010.

Kang, J., H. M. Park, Y. W. Kim, Y. H. Kim, S. Varghese, H. K. Seok, Y. G. Kim, and S. H. Kim. “Control of mesenchymal stem cell phenotype and differentiation depending on cell adhesion mechanism.” Eur Cell Mater 28 (November 25, 2014): 387–403. https://doi.org/10.22203/ecm.v028a27.

Kang, H., C. Wen, Y. Hwang, Y. R. V. Shih, M. Kar, S. W. Seo, and S. Varghese. “Biomineralized matrix-assisted osteogenic differentiation of human embryonic stem cells.” Journal of Materials Chemistry B 2, no. 34 (September 14, 2014): 5676–88. https://doi.org/10.1039/c4tb00714j.

Hwang, Yongsung, Samuel Suk, Yu-Ru Vernon Shih, Timothy Seo, Bin Du, Yun Xie, Ziyang Li, and Shyni Varghese. “WNT3A promotes myogenesis of human embryonic stem cells and enhances in vivo engraftment.” Sci Rep 4 (August 1, 2014): 5916. https://doi.org/10.1038/srep05916.

Caro-Diaz, E. J. E., A. Aung, J. Xu, S. Varghese, and E. A. Theodorakis. “Fusarisetins: structure-function studies on a novel class of cell migration inhibitors.” Organic Chemistry Frontiers 1, no. 2 (April 1, 2014): 135–39. https://doi.org/10.1039/c3qo00067b.

Shih, Yu-Ru V., YongSung Hwang, Ameya Phadke, Heemin Kang, Nathaniel S. Hwang, Eduardo J. Caro, Steven Nguyen, et al. “Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling.” Proc Natl Acad Sci U S A 111, no. 3 (January 21, 2014): 990–95. https://doi.org/10.1073/pnas.1321717111.

Lim, H. L., Y. Hwang, M. Kar, and S. Varghese. “Smart hydrogels as functional biomimetic systems.” Biomaterials Science 2, no. 5 (January 1, 2014): 603–18. https://doi.org/10.1039/c3bm60288e.

Hwang, Nathaniel S., Shyni Varghese, H Janice Lee, Zijun Zhang, and Jennifer Elisseeff. “Biomaterials directed in vivo osteogenic differentiation of mesenchymal cells derived from human embryonic stem cells.” Tissue Eng Part A 19, no. 15–16 (August 2013): 1723–32. https://doi.org/10.1089/ten.TEA.2013.0064.

Phadke, Ameya, YongSung Hwang, Su Hee Kim, Soo Hyun Kim, Tomonori Yamaguchi, Koichi Masuda, and Shyni Varghese. “Effect of scaffold microarchitecture on osteogenic differentiation of human mesenchymal stem cells.” Eur Cell Mater 25 (January 18, 2013): 114–29. https://doi.org/10.22203/ecm.v025a08.

Aung, A., and S. Varghese. “Traction stress as a modulator for protease dependent invasion of cancer cells.” In Food Pharmaceutical and Bioengineering Division 2013 Core Programming Area at the 2013 Aiche Annual Meeting Global Challenges for Engineering A Sustainable Future, 847–48, 2013.

Castro-Ceseña, A. B., E. E. Novitskaya, A. Phadke, S. Varghese, and J. McKittrick. “Isolation of collagen from cortical bovine bone for preparation of porous collagen sponges.” In Conference Proceedings of the Society for Experimental Mechanics Series, 5:73–78, 2013. https://doi.org/10.1007/978-1-4614-4427-5_11.

Chang, Chien-Wen, Yongsung Hwang, Dave Brafman, Thomas Hagan, Catherine Phung, and Shyni Varghese. “Engineering cell-material interfaces for long-term expansion of human pluripotent stem cells.” Biomaterials 34, no. 4 (January 2013): 912–21. https://doi.org/10.1016/j.biomaterials.2012.10.020.

Hwang, Yongsung, Samuel Suk, Susan Lin, Matthew Tierney, Bin Du, Timothy Seo, Aaron Mitchell, Alessandra Sacco, and Shyni Varghese. “Directed in vitro myogenesis of human embryonic stem cells and their in vivo engraftment.” PLoS One 8, no. 8 (2013): e72023. https://doi.org/10.1371/journal.pone.0072023.

Nguyen, Quynhhoa T., Yongsung Hwang, Albert C. Chen, Shyni Varghese, and Robert L. Sah. “Cartilage-like mechanical properties of poly (ethylene glycol)-diacrylate hydrogels.” Biomaterials 33, no. 28 (October 2012): 6682–90. https://doi.org/10.1016/j.biomaterials.2012.06.005.

Varghese, S., and C. Jamora. “Hydrogels: A versatile tool with a myriad of biomedical and research applications for the skin.” Expert Review of Dermatology 7, no. 4 (August 1, 2012): 315–17. https://doi.org/10.1586/edm.12.28.

Phadke, Ameya, Yu-Ru V. Shih, and Shyni Varghese. “Mineralized synthetic matrices as an instructive microenvironment for osteogenic differentiation of human mesenchymal stem cells.” Macromol Biosci 12, no. 8 (August 2012): 1022–32. https://doi.org/10.1002/mabi.201100289.

Soman, Pranav, Jin Woo Lee, Ameya Phadke, Shyni Varghese, and Shaochen Chen. “Spatial tuning of negative and positive Poisson's ratio in a multi-layer scaffold.” Acta Biomater 8, no. 7 (July 2012): 2587–94. https://doi.org/10.1016/j.actbio.2012.03.035.

Soman, P., D. Y. Fozdar, J. W. Lee, A. Phadke, S. Varghese, and S. Chen. “A three-dimensional polymer scaffolding material exhibiting a zero Poisson's ratio.” Soft Matter 8, no. 18 (May 14, 2012): 4946–51. https://doi.org/10.1039/c2sm07354d.

Phadke, Ameya, Chao Zhang, Bedri Arman, Cheng-Chih Hsu, Raghunath A. Mashelkar, Ashish K. Lele, Michael J. Tauber, Gaurav Arya, and Shyni Varghese. “Rapid self-healing hydrogels.” Proc Natl Acad Sci U S A 109, no. 12 (March 20, 2012): 4383–88. https://doi.org/10.1073/pnas.1201122109.

Varghese, S., and A. J. Engler. “Musculoskeletal cell mechanics.” In Orthopaedic Biomechanics, 301–23, 2012. https://doi.org/10.1201/b13733.